★ ★ ★ ★ ★
By far the best in Georgetown. The kindness and the professionalism speak for themselves — and Dr. O'Neill's expertise in women's health is unmatched.
Verified Google reviewWomen’s health & aesthetics · 2026
Your biology, mapped. Yourself, refined.
A physician-led practice in Georgetown where your skin, hormones, and metabolism are read as one system — and treated in the right order. Care for how you want to look and feel, for decades.
About us
We built the practice
We built the practice
we couldn’t find.
For most of the patients we’ve cared for over the past two decades, the care they wanted was already happening — but it was scattered. A dermatologist for the skin. A wellness clinic for the hormones. A med spa for the injectables. Each of them excellent, none of them speaking to each other — and the patient the only thread between them, repeating their history at every new front desk.
Bespoke was built on a different premise: that your hormones, your metabolism, and the surface of your skin are one continuous physiology — so the practice treating them should be one continuous conversation. The same hands that read your labs plan your injectables and track your skin. One chart. One trajectory. One team that knows your name.
If you’ve come for a single treatment, you’ll get our best version of it. If you’ve come for a practice that thinks across treatments — that’s what we’re built for, and the first visit is a conversation, not a procedure.
— Dr. Larissa O’Neill & Krista Singleton
Where to start
You can feel it
You can feel it
before you can name it.
You don’t need to know which treatment — or even which specialty. That’s what the first visit is for. Pick the one that sounds like you, and we’ll map it to a plan.
Hormones & energy
Tired, foggy,
running low
running low
The energy, drive, and sleep that slipped somewhere in your forties — measured first, then restored.
↗
Medical weight loss
The weight
won’t move
won’t move
Physician-led GLP-1, dosed to your labs and tracked on the InBody — not a brochure.
↗
Peptide therapy
Recovery takes
longer now
longer now
Signaling peptides for repair, deeper sleep, and the bounce-back you used to have.
↗
Injectables
Lines — and
lost volume
lost volume
Neuromodulators and filler, placed so you look rested, not done.
↗
Hair restoration
My hair is
thinning
thinning
Keralase™ and autologous PRP/PRF — before the part widens further.
↗
Regenerative medicine
I want to
age slower
age slower
Exosomes, PRF, and PDGF for cellular repair — investigational status disclosed in full.
↗
Lasers & skin
Tone, texture,
sun damage
sun damage
Laser, energy, peels and microneedling — sequenced across your year.
↗
HRT for women
Perimenopause
hit hard
hit hard
Hot flashes, mood, wrecked sleep — read on a panel and steadied, not brushed off.
↗
testosterone · estradiol · progesteroneData-guided restoration
The science underneath
The longevity
The longevity
side of aesthetics.
You’ve done the filler, the peels, the good skincare — and somewhere in your forties it stopped holding the way it used to. That isn’t the technique failing you. It’s the chemistry underneath it. Estradiol regulates collagen density; testosterone drives dermal thickness. When the foundation shifts, even excellent surface work has less to hold onto.
So we read what’s happening under your skin before we treat the surface of it — hormones, metabolism, the things a fifteen-minute visit never reaches. Measured first, restored, and only then refined.
First
Measure the chemistry
Then
Restore the foundation
Only then
Refine the surface
Your first visit
What to expect.
No menu pushed across the table. Your first visit is a conversation and a blood draw — the plan comes after, written from what we actually find.
01
We actually talk
A real sit-down — your history, what’s changed, what’s bothering you, what you want. Closer to an hour than fifteen minutes. No upsell.
02
We measure
A comprehensive blood panel — hormones, thyroid, metabolic markers — often drawn the same day. We don’t guess what’s going on; we look.
03
You get a real plan
Your clinician writes a plan from your actual results — and walks you through it together, before you commit to anything.
04
We stay with it
A re-check at six to eight weeks, then a steady rhythm — adjusting to how you feel and what the labs say, together.
In their words
Patients, on the practice.
Verified Google & in-office reviews from the last twelve months.
66 Google reviews
Real patients, real visits — read them all on Google
★ ★ ★ ★ ★
First clinic that took the time to actually run my labs before recommending a plan. Sleep is better, energy is back, and the skin work is finally holding.
Verified patientHormones & longevity · 2026
★ ★ ★ ★ ★
Krista is a precise injector who never overdoes it. I look like myself, just rested. That's exactly what I wanted.
Verified reviewInjectables · 2026
Start here
Begin with the panel,
Begin with the panel,
not the prescription.
Book online any time, or call and we’ll set up your first visit together. We hold real time for new patients — the first conversation is never rushed.
You’re invited
The season, celebrated.
Girls’ night out, date night, or just you and a friend. However you come, we’d love to see you there. No need to RSVP. Just come by.
Text us →